Table of Contents > Interactions & Depletions > Antipsychotics Print



Antipsychotics/Nutrient Depletion:
  • Coenzyme Q10 (CoQ10)Coenzyme Q10 (CoQ10): According to secondary sources, antipsychotics may reduce the natural production of CoQ10.
  • DHEADHEA:In men with mental disorders receiving antipsychotic drugs that had been medication-free for at least three months, there were lower serum levels of dehydroepiandrosterone sulfate (DHEAS) than in controls (10080231).
  • RiboflavinRiboflavin: Based on evidence from animal study, phenothiazine antipsychotic medications, such as chlorpromazine, may lower riboflavin levels (6626265). The study further indicates that phenothiazines may inhibit the incorporation of riboflavin into flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN).
  • SeleniumSelenium: Based on human study, it has been suggested that cardiac side effects associated with clozapine use may be related to low selenium concentrations (12630982, 8830067). It is unclear if assessment of selenium levels or selenium supplementation should be routine in patients taking this drug.

Copyright © 2011 Natural Standard (

The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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