LipidsLipids: Further clinical research has indicated a decrease in HDL-C levels and an increase in respective LDL-C/HDL-C/(apolipoprotein A/apolipoprotein B) lipid ratio (5.2% increase with androstenediol;10.5% increase with androstenedione) (3). Several other clinical studies have also shown that serum HDL cholesterol was reduced following androstenedione supplementation (5; 4; 15).
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