Table of Contents > Interactions & Depletions > Aloe (Aloe vera) Print

Aloe (Aloe vera)


Aloe/Nutrient Depletion:
  • GlucoseGlucose: Concomitant use of glucose-lowering agents with oral forms of aloe may increase hypoglycemic effects, according to preliminary human data (41; 40). In human research, compared to the placebo group following treatment, participants administered Aloe vera showed reduced mean glucose level (+5.2 ± 25.1% vs. -4.8 ± 14.7% change) (45).
  • LipidsLipids: Compared to baseline, participants receiving Aloe vera showed decreased levels of total cholesterol (15.4-15.5%), low-density lipoprotein (LDL) cholesterol (18.2-18.9%), and triglycerides (25.2-31.9%). Information regarding between-group differences was lacking (46). In human research, aloe has demonstrated further antilipemic effects (45; 64).
  • PotassiumPotassium: Based on the laxative properties of oral aloe latex, prolonged use may cause potassium depletion, metabolic alkalosis, and dehydration.
  • Vitamin CVitamin C: According to human research, aloe may slow the absorption of vitamin C (129).
  • Vitamin EVitamin E: According to human research, aloe may slow the absorption of vitamin E (129).

Copyright © 2011 Natural Standard (

The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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