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Scullcap (Scutellaria lateriflora)



Interactions

Scullcap/Drug Interactions:
  • Antidepressants, monoamine oxidase inhibitors (MAOIs)Antidepressants, monoamine oxidase inhibitors (MAOIs): In in vitro research, Scutellaria lateriflora inhibited the 5-HT(7) receptor, an action that seems to have antidepressant effects (2).
  • Antidepressants, selective serotonin reuptake inhibitors (SSRIs)Antidepressants, selective serotonin reuptake inhibitors (SSRIs): In in vitro research, Scutellaria lateriflora inhibited the 5-HT(7) receptor, an action that seems to have antidepressant effects (2).
  • AntispasmodicsAntispasmodics: According to secondary sources, scullcap may have antispasmodic effects.
  • HepatotoxinsHepatotoxins: According to human research, scullcap may cause liver damage (5).
  • AnxiolyticsAnxiolytics: In human research, Scutellaria lateriflora had anxiolytic effects (1). According to animal research, scullcap contains a flavonoid, baicalin, which is reported to bind to the benzodiazepine site of the GABA-A receptor (4).
  • BenzodiazepinesBenzodiazepines: In human research, Scutellaria lateriflora had anxiolytic effects (1). According to animal research, scullcap contains a flavonoid, baicalin, which is reported to bind to the benzodiazepine site of the GABA-A receptor (4).
  • Neurologic agentsNeurologic agents: According to secondary sources, high doses of scullcap may cause giddiness, stupor, confusion, and other symptoms suggestive of epilepsy.
  • SedativesSedatives: According to animal research, scullcap may have sedative effects (4).

Scullcap/Herb/Supplement Interactions:
  • Antidepressants, monoamine oxidase inhibitors (MAOIs)Antidepressants, monoamine oxidase inhibitors (MAOIs): In in vitro research, Scutellaria lateriflora inhibited the 5-HT(7) receptor, an action that seems to have antidepressant effects (2).
  • Antidepressants, selective serotonin reuptake inhibitors (SSRIs)Antidepressants, selective serotonin reuptake inhibitors (SSRIs): In in vitro research, Scutellaria lateriflora inhibited the 5-HT(7) receptor, an action that seems to have antidepressant effects (2).
  • AntispasmodicsAntispasmodics: According to secondary sources, scullcap may have antispasmodic effects.
  • AnxiolyticsAnxiolytics: In human research, Scutellaria lateriflora had anxiolytic effects (1). According to animal research, scullcap contains a flavonoid, baicalin, which is reported to bind to the benzodiazepine site of the GABA-A receptor (4).
  • HepatotoxinsHepatotoxins: According to human research, scullcap may cause liver damage (5).
  • Neurologic agentsNeurologic agents: According to secondary sources, high doses of scullcap may cause giddiness, stupor, confusion, and other symptoms suggestive of epilepsy.
  • SedativesSedatives: According to animal research, scullcap may have sedative effects (4).

Scullcap/Food Interactions:
  • Insufficient available evidence.

Scullcap/Lab Interactions:
  • Liver panelLiver panel: According to human research, scullcap may cause liver damage (5).

Copyright © 2011 Natural Standard (www.naturalstandard.com)


The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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