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Amaranth oil (Amaranthus L.)



Interactions

Amaranth/Drug Interactions:
  • Antidiabetic agentsAntidiabetic agents: Amaranth has been shown to decrease blood sugar levels in animals (13; 14).
  • AntihistaminesAntihistamines: According to secondary sources, amaranth may interact with antihistamines.
  • Antihypertensive agentsAntihypertensive agents: Amaranth has been shown to induce blood pressure lowering effects in patients with coronary heart disease (2; 3).
  • Antilipemic agents, HMG-CoA reductase inhibitorsAntilipemic agents, HMG-CoA reductase inhibitors: Amaranth has been shown to induce cholesterol lowering effects in patients with coronary heart disease (2) and in rats (8).
  • Immunomodulatory agentsImmunomodulatory agents: Amaranth has been shown to induce immunomodulatory effects in patients with ischemic heart disease and hyper-lipoproteinemia (9). Recent research suggests that squalene, a major constituent of amaranth, acts as an immunoadjuvant (25), suggesting that amaranth may possess some intrinsic immunostimulatory properties.
  • Nephrotoxic agentsNephrotoxic agents: Amaranth may contain high levels of oxalic acid.
  • Ocular agentsOcular agents: According to secondary sources, squalene, a lipid constituent of amaranth, may concentrate in the retina.

Amaranth/Herb/Supplement Interactions:
  • Amino acid containing supplementsAmino acid containing supplements: Consuming a meal consisting of amaranth alone may result in a post-meal drop in the essential amino acids leucine and threonine (47).
  • AntihistaminesAntihistamines: According to secondary sources, amaranth may interact with antihistamines.
  • AntilipemicsAntilipemics: Amaranth has been shown to induce cholesterol lowering effects in patients with coronary heart disease (2) and in rats (8).
  • Essential fatty acidsEssential fatty acids: Based on animal research, a diet consisting of raw and popped grain amaranth may result in an increase in linoleic acid (48).
  • Fiber supplementsFiber supplements: Amaranth reportedly contains high levels of fiber.
  • HypoglycemicsHypoglycemics: Amaranth has been shown to decrease blood sugar levels in animals (13; 14; 8).
  • HypotensivesHypotensives: Amaranth has been shown to induce blood pressure lowering effects in patients with coronary heart disease (2; 3).
  • Immunomodulatory herbs and supplementsImmunomodulatory herbs and supplements: Amaranth has been shown to induce immunomodulatory effects in patients with ischemic heart disease and hyper-lipoproteinemia (9). Recent research suggests that squalene, a major constituent of amaranth, acts as an immunoadjuvant (25), suggesting that amaranth may possess some intrinsic immunostimulatory properties.
  • Mineral supplementsMineral supplements: Amaranth reportedly contains high levels of calcium, iron, zinc, potassium, magnesium, and nickel. Thus, amaranth consumption may have additive effects on blood levels of minerals if taken with supplementary minerals. However, due to its high oxalic acid content, amaranth may also inhibit the absorption of calcium and zinc.
  • Nephrotoxic herbs and supplementsNephrotoxic herbs and supplements: Amaranth may contain high levels of oxalic acid.
  • Ocular herbs and supplementsOcular herbs and supplements: According to secondary sources, squalene, a lipid constituent of amaranth, may concentrate in the retina.

Amaranth/Food Interactions:
  • Amino acidsAmino acids: Consuming a meal consisting of amaranth alone may result in a post-meal drop in the essential amino acids leucine and threonine (47).
  • Essential fatty acidsEssential fatty acids: Based on animal research, a diet consisting of raw and popped grain amaranth may result in an increase in linoleic acid (48).
  • Fiber supplementsFiber supplements: Amaranth reportedly contains high levels of fiber.
  • ProbioticsProbiotics: In humans, combination of amaranth and a probiotic sour milk product resulted in a decrease in cardiovascular disease risk factors (10).

Amaranth/Lab Interactions:
  • Blood pressureBlood pressure: Amaranth has been shown to induce blood pressure lowering effects in patients with coronary heart disease (2; 3).
  • Lipid panelLipid panel: Amaranth has been shown to reduce serum cholesterol and triglyceride levels, in addition to the fatty acid composition of the membranes of erythrocytes (3).
  • Serum electrolytesSerum electrolytes: Amaranth reportedly contains high levels of calcium, iron, zinc, potassium, magnesium, and nickel. Thus, amaranth consumption may interfere with lab tests that rely on baseline levels of these minerals. Due to its high oxalic acid content, amaranth may also inhibit the absorption of calcium and zinc.
  • Serum glucoseSerum glucose: Amaranth has been shown to lower blood glucose levels in animals (13; 14).

Copyright © 2011 Natural Standard (www.naturalstandard.com)


The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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