Table of Contents > Interactions & Depletions > Acacia Print



Acacia/Drug Interactions:
  • AmoxicillinAmoxicillin: Acacia may affect the absorption of amoxicillin when taken concurrently; doses should be separated by at least four hours (50).
  • Anticancer drugsAnticancer drugs: Use of acacia as a surfactant may increase the intestinal absorption of some anticancer drugs through P-glycoprotein (P-gp) inhibition and thus improve drug bioavailability for P-gp substrate (54).
  • Ethanol (alcohol)Ethanol (alcohol): Mixing acacia with a substance containing more than 50% concentration of ethyl alcohol may cause acacia to become insoluble.
  • IronIron: Acacia can be gelatinized by solutions of ferric iron salts.
  • Oral drugsOral drugs: Theoretically, the fiber in acacia may impair the absorption of oral drugs.

Acacia/Herb/Supplement Interactions:
  • Oral herbs and supplementsOral herbs and supplements: Theoretically, the fiber in acacia may impair the absorption of oral herbs and supplements.
  • Tannin-containing herbs and supplementsTannin-containing herbs and supplements: Theoretically, tannins from Acacia catechu L. plant may contribute to oral and esophageal cancer when combined with other substances that also contain high amounts of tannins (53).

Acacia/Food Interactions:
  • Alcohol or alcoholic solutionAlcohol or alcoholic solution: Acacia gum used with alcohol or alcoholic solution may precipitate from suspensions.

Acacia/Lab Interactions:
  • Insufficient available evidence.

Copyright © 2011 Natural Standard (

The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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